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What are the best Squad Combinations in Mass Effect?

What are the best Squad Combinations in Mass Effect?

Mass Effect stands at the pinnacle of action RPG due to its excellent quest design, storyline, mechanics, and memorable characters. Speaking of the characters, the game allows you to take two of these available companions to any mission. In this article, we will try to make this decision easy for you by explaining what are the best squad combinations in Mass Effect and why.

The best squad combination in Mass Effect are:

  • Garrus And Ashley
  • Garrus And Tali
  • Tali And Liara
  • Ashley And Wrex
  • Liara And Kaidan
  • Ashley And Liara
  • Wrex And Tali
  • Ashley And Kaidan
  • Wrex And Garrus

Garrus And Ashley

Garrus Vakarian - Mass Effect Squad Combinations
Garrus Vakarian
  • Intelligence
  • Marksmanship
  • Concussive Shot
  • Armor-Piercing Rounds
Ashley Madeline Williams - Mass Effect Squad Combinations
Ashley Madeline Williams
  • Marksmanship
  • Weapons training
  • First aid
  • Concussive shot
  • Disruptor Ammo
  • Inferno Grenade

If you are looking for a pair that can cover your back from a long distance then Garrus and Ashely are the ones to pick. They both are quite deadly with a sniper and have decent damage output. When leveled up correctly and with a good firearm in their hand, they will easily be picking off enemies before they can reach you.

Garrus also brings a slew of Teck Skills with him which can come in handy. However, you might have to invest in some Biotic abilities as they both are lacking in this domain. Although they can make up for it with their exceptional firepower.

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Garrus And Tali

Garrus Vakarian - Mass Effect Squad Combinations
Garrus Vakarian
  • Intelligence
  • Marksmanship
  • Concussive Shot
  • Armor-Piercing Rounds
Tali'Zorah nar Rayya - Mass Effect Squad Combinations
Tali’Zorah nar Rayya
  • High IQ
  • Extensive AI knowledge
  • Defense drones
  • Skilled in pistols and shotguns

If tech is more up your alley then Garrus and Tali are the prime candidates to take along. They both are quite skilled in tech abilities. These powers are such a blessing when you are up against those dreaded shielded Geth.

They both also have other complimentary playstyles too. Garrus is a great long-range combatant while Tali has close-range expertise. The only problem with these two is their inadequacy in biotics. You can counter this by opting for either Adept, Vanguard, or a Sentinel Shepard.

Tali And Liara

Liara T'Soni - Mass Effect Squad Combinations
Liara T’Soni
  • Firearms (heavy pistols and sub-machine guns)
  • Biotics
  • Sciences
  • Archaeology
  • Prothean History and Culture
Tali'Zorah nar Rayya - Mass Effect Squad Combinations
Tali’Zorah nar Rayya
  • High IQ
  • Extensive AI knowledge
  • Defense drones
  • Skilled in pistols and shotguns

If you are looking for specialists rather than a jack of all trades then Tali and Liara are the masters of their respective trades. Tali is a tech whizz who is convenient for dealing with Geth while also hacking locked crates. Liara is a biotic maestro, which will help you in those dangerous sections of this game. These two will have these bases covered hence you will be at ease.

However, you will have to be the primary damage dealer with these two by your side as they both are weak in this aspect. Tali can hold her own ground in certain situations but you must be ready to protect these fine ladies.

Ashley And Wrex

Ashley Madeline Williams
Ashley Madeline Williams
  • Marksmanship
  • Weapons training
  • First aid
  • Concussive shot
  • Disruptor Ammo
  • Inferno Grenade
Urdnot Wrex
Urdnot Wrex
  • Massive strength
  • Biotics

If you want to take more of a “backseat from the action” approach and let your squad do all the dirty work then Ashely and Wrex are the perfect protectors. Just looking at Wrex, you can figure out this brute comes with built-in strength and there is no shortage of it.

As for Ashley, she does require a bit of tinkering to reach that tank status. While upgrading, just focus on the stats that boost her tanky-ness all the while equipping her with the strongest gear you can find. If done right, you can just sit back relax and let these two wreak havoc. Don’t become too lazy though and fill the support role.

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Liara And Kaidan

Liara T'Soni - Mass Effect Squad Combinations
Liara T’Soni
  • Firearms (heavy pistols and sub-machine guns)
  • Biotics
  • Sciences
  • Archaeology
  • Prothean History and Culture
Kaidan Alenko - Mass Effect Squad Combinations
Kaidan Alenko
  • Biotics
  • Technology
  • Weapons mastery

Since the first game in the series has made biotics a bit OP, Liara and Kaidan are the pair to take advantage of this slip-up by Bioware. With that said, these two companions are the pundits of biotics. And owing to this, these two can be considered the OP deadly duo.

They both have great biotic powers like lift, barrier, and Liaria’s singularity. They both bring tech talent to the table as well which is always a plus. You just have to be the heavy lifter in this squad (damage-wise) so bulk up Shepard.

Ashley And Liara

Ashley Madeline Williams - Mass Effect Squad Combinations
Ashley Madeline Williams
  • Marksmanship
  • Weapons training
  • First aid
  • Concussive shot
  • Disruptor Ammo
  • Inferno Grenade
Liara T'Soni - Mass Effect Squad Combinations
Liara T’Soni
  • Firearms (heavy pistols and sub-machine guns)
  • Biotics
  • Sciences
  • Archaeology
  • Prothean History and Culture

Although these two women are romantic rivals fighting for that sweet Shepard loving, they both have talents that complement each other. Hence, embarking on missions with this tense love triangle is fairly effective.

Tali can lift enemies in the air with her abilities while Ashely can gun down these fish in a barrel with ease. This strategy will prove mighty useful for the end boss battle of the game. The Shepard in those trio should be tech-based so that you can add to the team synergy and even open those pesky containers.

Wrex And Tali

Urdnot Wrex - Mass Effect Squad Combinations
Urdnot Wrex
  • Massive strength
  • Biotics
Tali'Zorah nar Rayya - Mass Effect Squad Combinations
Tali’Zorah nar Rayya
  • High IQ
  • Extensive AI knowledge
  • Defense drones
  • Skilled in pistols and shotguns

If you are the one who prefers dealing with enemies up close and personal then Wrex and Tali are the wrecking balls at your disposal. Their hands-on approach makes them quite deadly in close-quarter engagements with their love for all shotguns. Very helpful against husks and thorian creepers.

On top of this “in your face” ace-ness of these two, they have other advantages as well. Tali is a tech genius and Wrex has the power of the mighty biotics. Just remember to make your Shepard into an infiltrator or a soldier so that you can be the long-range damage dealer.

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Ashley And Kaidan

Ashley Madeline Williams - Mass Effect Squad Combinations
Ashley Madeline Williams
  • Marksmanship
  • Weapons training
  • First aid
  • Concussive shot
  • Disruptor Ammo
  • Inferno Grenade
Kaidan Alenko - Mass Effect Squad Combinations
Kaidan Alenko
  • Biotics
  • Technology
  • Weapons mastery

On the surface, this seems like a boring homo-sapien-only pairing but these two original squadmates can make an excellent team. This can become a tank and her support kind of duo which leaves you to experiment with other types of Shepard builds. These two can sustain themselves pretty well.

As mentioned before, you will have to take some time out to build Ashley up as a tank with proper stats upgrading and deadly gear. Alenko with his tech and biotic skills can be the ace up Ashley’s sleeve with his immaculate support.

Wrex And Garrus

Urdnot Wrex - Mass Effect Squad Combinations
Urdnot Wrex
  • Massive strength
  • Biotics
Garrus Vakarian - Mass Effect Squad Combinations
Garrus Vakarian
  • Intelligence
  • Marksmanship
  • Concussive Shot
  • Armor-Piercing Rounds

This squad is the go-to pair for many Mass Effect fans as they are the most cherished of all companions. However, these two aliens can also dominate the battlefield with their incredible array of abilities.

Wrex is a close-quarter pro while Garrrus has long-range capability with his sniper. And with both of them having an assault rifle in hand at all times, the mid-range is no big deal.

The ranges of combat are not only it, they deal deadly damage from the weapon they hold as well. The cherry on top is that Wrex has the biotic talent and Garrus has the tech skills to cover all the bases. This is the best squad in the game and is a no-brainer when going on your next mission.


Mass Effect offers many squad combinations that work really well together. This does make the decision of which pair to choose even more difficult. But if you stick to the ones we have recommended then be sure that you are in the right hands. Just try to adjust your Shepard to the team and you are good to go.